<?xml version="1.0" encoding="UTF-8"?>
<rss version="2.0"
	xmlns:content="http://purl.org/rss/1.0/modules/content/"
	xmlns:wfw="http://wellformedweb.org/CommentAPI/"
	xmlns:dc="http://purl.org/dc/elements/1.1/"
	xmlns:atom="http://www.w3.org/2005/Atom"
	xmlns:sy="http://purl.org/rss/1.0/modules/syndication/"
	xmlns:slash="http://purl.org/rss/1.0/modules/slash/"
	>

<channel>
	<title>Drug Development Consultant &#38; Regulatory Consultant &#187; discovery</title>
	<atom:link href="http://www.damienbove.com/category/discovery/feed/" rel="self" type="application/rss+xml" />
	<link>http://www.damienbove.com</link>
	<description>Damien Bove Shares The Expertise</description>
	<lastBuildDate>Thu, 09 Feb 2012 16:32:39 +0000</lastBuildDate>
	<language>en</language>
	<sy:updatePeriod>hourly</sy:updatePeriod>
	<sy:updateFrequency>1</sy:updateFrequency>
	<generator>http://wordpress.org/?v=3.3.1</generator>
		<item>
		<title>EMA Announces Drug Development Modeling and Simulation Workshop</title>
		<link>http://www.damienbove.com/2011/09/09/ema-announces-drug-development-modeling-and-simulation-workshop/</link>
		<comments>http://www.damienbove.com/2011/09/09/ema-announces-drug-development-modeling-and-simulation-workshop/#comments</comments>
		<pubDate>Fri, 09 Sep 2011 07:28:19 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[discovery]]></category>
		<category><![CDATA[modeling]]></category>
		<category><![CDATA[simulation]]></category>

		<guid isPermaLink="false">http://www.damienbove.com/?p=3048</guid>
		<description><![CDATA[The objective of the workshop is to discuss the role and scope of modelling and simulation in drug-development both from the developer’s and the regulator’s perspectives. Registration by invitation only. Registration open until 14/10/2011. Places limited. <a href="http://www.damienbove.com/2011/09/09/ema-announces-drug-development-modeling-and-simulation-workshop/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
			<content:encoded><![CDATA[<h1>EMA Announces Drug Development Modeling and Simulation Workshop</h1>
<p>Full Text <a title="EMA Meeting" href="http://www.ema.europa.eu/ema/index.jsp?curl=pages/news_and_events/events/2011/07/event_detail_000440.jsp&amp;mid=WC0b01ac058004d5c3&amp;murl=menus/news_and_events/news_and_events.jsp&amp;jsenabled=true" target="_blank">Here</a></p>
<p>The objective of the workshop is to discuss the role and scope of  modelling and simulation in drug-development both from the developer’s  and the regulator’s perspectives. Registration by invitation only.  Registration open until 14/10/2011. Places limited.</p>
<p><!-- Place this tag where you want the +1 button to render --><br />
<g:plusone></g:plusone></p>
<p><!-- Place this tag after the last plusone tag --><br />
<script type="text/javascript">
  (function() {
    var po = document.createElement('script'); po.type = 'text/javascript'; po.async = true;
    po.src = 'https://apis.google.com/js/plusone.js';
    var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(po, s);
  })();
</script></p>
<div id="fb-root"></div>
<p><script src="http://connect.facebook.net/en_US/all.js#appId=194100293982344&amp;xfbml=1"></script><fb:like href="http://www.damienbove.com" send="true" width="450" show_faces="true" font=""></fb:like></p>
<h2>For Assistance with<a title="Drug,Biotechnology,Device Development Consultancy" href="http://www.damienbove.com/drug-development-and-planning-services/" target="_blank"> Product Development Planning </a> Click Here</h2>
<p>Damien Bové is THE Drug Development and Regulatory Consultant (pharmaceutical or biotechnology), I work with my clients to define a drug development target, define a drug development strategy, define a regulatory strategy or define a commercial strategy. Our clients are generally raising funds or looking to license out their technology and we help them achieve it. If you want to know more don’t hesitate to get in touch.</p>
<h1>Avoid Expensive Mistakes, Keep On Top of New and Changing Regulations for Free!</h1>
<p><!-- VZAAR START --></p>
<div class="vzaar_media_player"><object id="video" classid="clsid:d27cdb6e-ae6d-11cf-96b8-444553540000" width="462" height="266" codebase="http://download.macromedia.com/pub/shockwave/cabs/flash/swflash.cab#version=6,0,40,0"><param name="data" value="http://view.vzaar.com/314932.flashplayer" /><param name="allowScriptAccess" value="always" /><param name="allowFullScreen" value="true" /><param name="wmode" value="transparent" /><param name="flashvars" value="endText=Don%27t+forget+to+sign+up+for+our+FREE+regulatory+watch+newsletter%21&amp;colourSet=orange&amp;endLink=www.damienbove.com&amp;brandText=IDA+Consultants+-+Damien+Bove&amp;autoplay=true&amp;brandLink=www.damienbove.com" /><param name="src" value="http://view.vzaar.com/314932.flashplayer" /><param name="allowfullscreen" value="true" /><embed id="video" type="application/x-shockwave-flash" width="462" height="266" src="http://view.vzaar.com/314932.flashplayer" flashvars="endText=Don%27t+forget+to+sign+up+for+our+FREE+regulatory+watch+newsletter%21&amp;colourSet=orange&amp;endLink=www.damienbove.com&amp;brandText=IDA+Consultants+-+Damien+Bove&amp;autoplay=true&amp;brandLink=www.damienbove.com" wmode="transparent" allowfullscreen="true" allowscriptaccess="always" data="http://view.vzaar.com/314932.flashplayer"></embed></object></div>
<p><!-- VZAAR END --></p>
<p>Sign up for the most value add free newsource you can get for free.  We spend a huge amount of time and effort monitoring the main drug / device regulators websites for changes in the regulatory environment, and capture between <em>20 and 40 new regulations, rules and initiatives each month</em>, and summaries them in a fantastic <strong>FREE monthly Regulatory and Market Round Up</strong>. You can Un-Subscribe at any time and we don not share your details with anybody. You can&#8217;t afford to miss out on this service. <em>Just fill in the form below</em>.</p>
<div id="formContainer">
<h2 class="widgettitle">Fill Out the Short Form Below&#8230;</h2>
<form class="cform" action="http://www.damienbove.com/cgi-bin/arp3/arp3-formcapture.pl" method="post">
<ol class="cf-ol">
<li id="li--1"> <label for="cf_field_1"><span>First name</span></label><br />
<input class="single fldrequired" name="first_name" size="20" type="text" /> <span class="reqtxt">(required)</span></li>
<li id="li--2"> <label><span>Phone #1</span></label><br />
<input class="single fldemail fldrequired" name="phone1" size="20" type="text" /></li>
<li id="li--3"> <label><span>E-mail address</span></label><br />
<input class="single" name="email" size="20" type="text" /> <span class="emailreqtxt">(valid email required)</span></li>
</ol>
<input name="subscription_type" type="hidden" value="E" />
<p class="cf-sb">
<input id="sendbutton" class="sendbutton" type="submit" value="Yes Please, Sign Me Up Damien!" /></p>
<input name="id" type="hidden" value="7" />
<input name="extra_ar" type="hidden" />
</form>
</div>
<p><em>“Please note that the pages on this website are designed to provide you with general information only. We make no warranties, representations or undertakings about any of its content. This includes the completeness, accuracy and fitness for any particular purpose, or the content of any third party site referred to or accessed through it. You are personally responsible for ensuring that the information is correct and we will not be held liable or accountable for any mistakes that occur.”</em></p>
]]></content:encoded>
			<wfw:commentRss>http://www.damienbove.com/2011/09/09/ema-announces-drug-development-modeling-and-simulation-workshop/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Open Access Therapeutic Drug Targets Database Launched</title>
		<link>http://www.damienbove.com/2010/06/21/open-access-therapeutic-drug-targets-database-launched/</link>
		<comments>http://www.damienbove.com/2010/06/21/open-access-therapeutic-drug-targets-database-launched/#comments</comments>
		<pubDate>Mon, 21 Jun 2010 08:47:33 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[discovery]]></category>
		<category><![CDATA[database]]></category>
		<category><![CDATA[target]]></category>

		<guid isPermaLink="false">http://www.damienbove.com/?p=1473</guid>
		<description><![CDATA[A comprehensive database of therapeutic drug targets extracted from patents or patent applications, Sciclips has launched a unique, comprehensive and publicly accessible database on therapeutic drug targets.  <a href="http://www.damienbove.com/2010/06/21/open-access-therapeutic-drug-targets-database-launched/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
			<content:encoded><![CDATA[<h1>Open Access Therapeutic Drug Targets Database Launched</h1>
<p>Direct Access <a title="Drug Database" href="http://www.sciclips.com/sciclips/drug-targets-main.do " target="_blank">Here</a></p>
<p>A comprehensive database of therapeutic drug targets extracted from patents or patent applications, Sciclips has launched a unique, comprehensive and publicly accessible database on therapeutic drug targets. This database contains drug targets reported in US patents or US/International patent applications. The drug targets are classified according to specific drug types (e.g. small molecule drugs, protein drugs, antibody drugs, siRNA drugs, miRNA drugs etc.) and disease types. The assays and methods used for characterizing each drug targets are listed as well. In addition to this, all the drug targets are linked to PubMed, Google Scholar, GeneBank, UniProt, USPTO database, WO(PCT) database and Google Patents.</p>
<p>SciClips’ therapeutic drug target database is a valuable resource for biomedical and pharmaceutical researchers around the world. This one-of-a-kind database will help scientists to search for drug target/s of their choice from a huge database containing -4000 drug targets which are linked to their respective disease/s types. The database helps the researchers with the ability to search original patent/s or patent application/s linked to the particular drug target to get more information.</p>
<h2>Click Here for <a title="Drug Development Services" href="http://www.damienbove.com/drug-development-and-planning-services/pharmabiotech-development-services/" target="_self">Drug Development Services</a></h2>
<p>Damien Bové is THE Drug Development and Regulatory Consultant (pharmaceutical or biotechnology), I work with my clients to define a drug development target, define a drug development strategy, define a regulatory strategy or define a commercial strategy. Our clients are generally raising funds or looking to license out their technology and we help them achieve it. If you want to know more don’t hesitate to get in touch.</p>
<h1>Avoid Expensive Mistakes, Keep On Top of New and Changing Regulations for Free!</h1>
<p>Sign up for the most value add free newsource you can get for free.  We spend a huge amount of time and effort monitoring the main drug / device regulators websites for changes in the regulatory environment, and capture between <em>20 and 40 new regulations, rules and initiatives each month</em>, and summaries them in a fantastic <strong>FREE monthly Regulatory and Market Round Up</strong>. You can Un-Subscribe at any time and we don not share your details with anybody. You can&#8217;t afford to miss out on this service. <em>Just fill in the form below</em>.</p>
<form action="http://www.damienbove.com/cgi-bin/arp3/arp3-formcapture.pl" method="POST">
<div>
<p>First name</p>
<input name="first_name" size="20" type="text" />
</div>
<div>
<p>Phone #1</p>
<input name="phone1" size="20" type="text" />
</div>
<div>
<p>E-mail address</p>
<input name="email" size="20" type="text" />
</div>
<input name="subscription_type" type="hidden" value="E" />
<div>
<input type="submit" value="Yes Please, Sign Me Up!" /></div>
<input name="id" type="hidden" value="7" />
<div id="attachment_191" class="wp-caption aligncenter" style="width: 525px"><a href="http://www.damienbove.com/free-strategic-review/"><img class="size-full wp-image-191" title="Free Strategy Consultation - Biotech Pharma Regualtory" src="http://www.damienbove.com/wordpress/wp-content/uploads/2009/04/ida_consultants_freestrategyconsultation_515x64.jpg" alt="ida consultants freestrategyconsultation 515x64 Open Access Therapeutic Drug Targets Database Launched " width="515" height="64" /></a><p class="wp-caption-text">Free Strategy Consultation - Biotech Pharma Regualtory</p></div>
<input name="extra_ar" type="hidden" value="|2" />
</form>
<p><em>“Please note that the pages on this website are designed to provide you with general information only. We make no warranties, representations or undertakings about any of its content. This includes the completeness, accuracy and fitness for any particular purpose, or the content of any third party site referred to or accessed through it. You are personally responsible for ensuring that the information is correct and we will not be held liable or accountable for any mistakes that occur.”</em></p>
<p><em><a href="http://www.damienbove.com/how-to-write-a-business-plan/"><img class="aligncenter size-full wp-image-640" title="How To Write A Business Plan" src="http://www.damienbove.com/wordpress/wp-content/uploads/2009/07/ida_100programme_515x64_LowRes.jpg" alt="ida 100programme 515x64 LowRes Open Access Therapeutic Drug Targets Database Launched " width="515" height="64" /></a><br />
</em></p>
]]></content:encoded>
			<wfw:commentRss>http://www.damienbove.com/2010/06/21/open-access-therapeutic-drug-targets-database-launched/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
		<item>
		<title>Drug Development &#8211; Logic Models of Pathway Biology</title>
		<link>http://www.damienbove.com/2009/07/03/drug-development-logic-models-of-pathway-biology/</link>
		<comments>http://www.damienbove.com/2009/07/03/drug-development-logic-models-of-pathway-biology/#comments</comments>
		<pubDate>Fri, 03 Jul 2009 07:33:13 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[clinical]]></category>
		<category><![CDATA[discovery]]></category>
		<category><![CDATA[Fund raising]]></category>
		<category><![CDATA[Uncategorized]]></category>
		<category><![CDATA[drug development]]></category>
		<category><![CDATA[drug discovery]]></category>
		<category><![CDATA[indication selection]]></category>
		<category><![CDATA[therapeutic pathways]]></category>

		<guid isPermaLink="false">http://www.damienbove.com/?p=427</guid>
		<description><![CDATA[s part of our drug development consultancy we often investigate alternative indications for technologies, we progress through the therapeutic pathway and think about where this drug/biological may have an effect be that positive or negative <a href="http://www.damienbove.com/2009/07/03/drug-development-logic-models-of-pathway-biology/">Continue reading <span class="meta-nav">&#8594;</span></a>]]></description>
			<content:encoded><![CDATA[<p>As part of our drug development consultancy we often investigate alternative indications for technologies, we progress through the therapeutic pathway and think about where this drug/biological may have an effect be that positive or negative. Having just read an interesting article in Drug Discovery Today (Vol 13 (9/10) May 2008) by Watterson, Marshall and Ghazal. The article titles &#8220;logic models of pathway biology&#8221; looks at complex living systems and how logic can be used to determine how a drug will interact with the complex biologic pathways.</p>
<p>They describe computational models that comb the pathways for the upstream interactions that control downstream behaviour, allowing them to identify lead candidates for therapeutic treatments. They take the kind of literature based approach we follow to the next level studying proteins, genes and gene products.</p>
<p>Biological pathways can comprise one or more of the following:</p>
<ul>
<li>Metabolic pathways</li>
<li>Molecular interactions</li>
<li>Gene regulatory networks</li>
<li>Signalling pathways</li>
</ul>
<p>Whilst the researchers hear focus on Boolean Logic and computer modeling we hold that a good review of possible effects and pathways can be tackled using literature searches and scientific hypothesis. I would propose that any drug or biological agent should undergo a similar scrutiny to find new opportunities and highlight potential issues.</p>
<p>Where we look at biological systems they magnify the process, the target the same, an understanding of how a system operates.  It is an interesting article that is well worth reading.</p>
<p class="MsoNormal">If you would like more detail in this area please get in touch with Damien Bové damien.bove@idaconsultants.com</p>
<p>Damien Bové works as a drug development consultant (pharmaceutical or biotechnology) and regulatory consultant, we work with our clients to define a drug  development target, define a drug development strategy, define a regulatory strategy or define a commercial strategy. Our clients are generally raising funds or looking to license out their technology and we help them achieve it. If you want to know more don’t hesitate to get in touch.</p>
<dl id="attachment_191" class="wp-caption aligncenter" style="display: block; margin-left: auto; margin-right: auto; text-align: center; background-color: #f3f3f3; padding-top: 4px; margin-top: 10px; margin-bottom: 10px; -webkit-border-top-right-radius: 3px 3px; -webkit-border-top-left-radius: 3px 3px; -webkit-border-bottom-left-radius: 3px 3px; -webkit-border-bottom-right-radius: 3px 3px; border: 1px solid #dddddd;">
<dt class="wp-caption-dt"><a href="http://www.damienbove.com/?page_id=183"><img class="size-full wp-image-191" style="padding: 0px; margin: 0px; border: 0px none initial;" title="Free Strategy Consultation - Biotech Pharma Regualtory" src="http://www.damienbove.com/wordpress/wp-content/uploads/2009/04/ida_consultants_freestrategyconsultation_515x64.jpg" alt="ida consultants freestrategyconsultation 515x64 Drug Development   Logic Models of Pathway Biology" width="515" height="64" /></a></dt>
</dl>
<p><strong>Grow your Expertise for Free</strong></p>
<p><span style="font-weight: normal; font-size: 13px; ">As you know this website is a great resource for keeping up to date with developments and regulations, why not get our </span><span style="font-size: 13px; "><strong>FREE</strong></span><span style="font-weight: normal; font-size: 13px; "><strong> monthly regulatory and market round up</strong></span><span style="font-weight: normal; font-size: 13px; ">. You can un-subscribe at any time and we do not share your details with anybody.</span></p>
<form action="http://damienbove.createsend.com/t/y/s/thtylt/" method="post">
<div><label for="name">First Name:</label></p>
<input id="name" name="cm-name" type="text" /></div>
<div><label for="thtylt-thtylt">Email:</label></div>
<div>
<input id="thtylt-thtylt" name="cm-thtylt-thtylt" type="text" />
<input type="submit" value="Subscribe" /></div>
</form>
<div id="_mcePaste" style="overflow: hidden; position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px;">This guideline ap</div>
<div id="_mcePaste" style="overflow: hidden; position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px;">recombinant vaccines for the prevention and treatment of infectious disease, and provides guidance on quality, non-clinical and clinical aspects.</div>
]]></content:encoded>
			<wfw:commentRss>http://www.damienbove.com/2009/07/03/drug-development-logic-models-of-pathway-biology/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
		</item>
	</channel>
</rss>

